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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKB
All Species:
22.73
Human Site:
T50
Identified Species:
38.46
UniProt:
Q96GD4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GD4
NP_004208.2
344
39280
T50
S
R
S
N
V
Q
P
T
A
A
P
G
Q
K
V
Chimpanzee
Pan troglodytes
XP_511856
395
44529
T101
S
R
C
N
V
Q
P
T
A
A
P
G
Q
K
V
Rhesus Macaque
Macaca mulatta
XP_001118154
562
62706
T268
S
R
S
N
V
Q
P
T
A
A
P
G
Q
K
V
Dog
Lupus familis
XP_849906
346
39574
T50
S
R
S
N
G
Q
P
T
A
A
P
G
Q
K
V
Cat
Felis silvestris
Mouse
Mus musculus
O70126
345
39306
T50
N
R
S
N
S
Q
S
T
A
A
P
G
Q
K
L
Rat
Rattus norvegicus
O55099
343
39216
T50
N
R
S
N
S
Q
S
T
A
V
P
G
Q
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
R50
F
G
N
V
Y
L
A
R
E
K
Q
S
K
F
I
Chicken
Gallus gallus
XP_425725
409
46456
S120
A
K
S
S
E
A
D
S
V
S
K
Q
K
N
E
Frog
Xenopus laevis
Q6DE08
361
41717
R66
A
S
S
S
V
P
G
R
V
A
V
S
T
E
M
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
I50
S
N
S
K
V
L
S
I
D
D
F
D
I
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
E54
D
W
S
P
R
D
F
E
M
G
A
H
L
G
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
F54
A
R
T
K
T
G
H
F
H
V
A
I
K
V
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M077
294
33954
L47
G
K
F
G
H
V
Y
L
A
R
E
K
R
S
N
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
P77
E
S
S
K
I
P
S
P
I
R
K
A
T
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
60.3
91.3
N.A.
84.9
84.5
N.A.
61.9
56.9
67.5
66.5
N.A.
44.4
N.A.
53.4
N.A.
Protein Similarity:
100
86.3
60.6
95
N.A.
91.5
90.4
N.A.
72
66.5
78.6
76.1
N.A.
62.5
N.A.
65.1
N.A.
P-Site Identity:
100
93.3
100
93.3
N.A.
73.3
66.6
N.A.
0
6.6
20
20
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
86.6
80
N.A.
20
46.6
46.6
20
N.A.
6.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.9
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68
59.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
0
8
8
0
50
43
15
8
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
8
0
8
8
0
8
0
0
0
% D
% Glu:
8
0
0
0
8
0
0
8
8
0
8
0
0
8
8
% E
% Phe:
8
0
8
0
0
0
8
8
0
0
8
0
0
8
0
% F
% Gly:
8
8
0
8
8
8
8
0
0
8
0
43
0
15
0
% G
% His:
0
0
0
0
8
0
8
0
8
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
8
0
0
8
8
0
8
% I
% Lys:
0
15
0
22
0
0
0
0
0
8
15
8
22
43
0
% K
% Leu:
0
0
0
0
0
15
0
8
0
0
0
0
8
0
22
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% M
% Asn:
15
8
8
43
0
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
0
0
0
8
0
15
29
8
0
0
43
0
0
0
0
% P
% Gln:
0
0
0
0
0
43
0
0
0
0
8
8
43
0
0
% Q
% Arg:
0
50
0
0
8
0
0
15
0
15
0
0
8
0
15
% R
% Ser:
36
15
72
15
15
0
29
8
0
8
0
15
0
15
8
% S
% Thr:
0
0
8
0
8
0
0
43
0
0
0
0
15
0
0
% T
% Val:
0
0
0
8
36
8
0
0
15
15
8
0
0
8
29
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _